Figure 7.

Light and dark viability of HeLa and NHDF cells in the presence of free and encapsulated forms of Cholosens: (a) cell viability depending on the number of Cholosens-loaded [DS/PArg]₄ microcapsules (intact or heated) in the culture medium; (b) comparative effect of the free and encapsulated forms of Cholosens after light irradiation. HeLa/pure and NHDF/pure refer to the cells untreated with any form of Cholosens. Corresponding data on the viability of non-irradiated HeLa and NHDF cells grown without any of encapsulated or free forms of Cholosens were taken as 100%. The respective Student’s t-test results are shown in Tables S2–S6. * p < 0.05, ** p < 0.01 when compared heated vs. intact capsules (a), and encapsulated forms of Cholosens vs. free drug (b). The respective IC50 values for each drug form are shown in Table S10.