Table 1.
Demographic and clinical characteristic of patients with CD, UC, or Ctr. The statistical difference was analyzed by the Mann–Whitney U-test. p value < 0.05 was considered significant.
| Characteristic | UC | CD | Ctr | p |
|---|---|---|---|---|
| N° of pts | 39 | 34 | 24 | NA |
| Age (median years) | 14 (4–17) | 13.5 (6–17) | 11.5 (4–17) | NS |
| Gender (male) | 18 | 22 | 13 | NS |
| Disease activity index – median (range) |
PUCAI 45 (10–75) |
PCDAI 25 (5–55) |
NA | NA |
| Paris classification (No. of pts) | ||||
| Location - L1/L2/L3 | NA | 17/3/14 | NA | NA |
| Behavior - B1/B2/B2B3 | NA | 11/20/3 | NA | NA |
| Growth - G0/G1 | NA | 22/12 | NA | NA |
| Extent - E1/E2/E3/E4 | 9/8/9/13 | NA | NA | NA |
| SES-CD | NA | 11.5 (0–31) | NA | NA |
| Mayo endoscopic score I/II/III | 6/16/17 | NA | NA | NA |
| ESR (mm/h); median (range) | 17 (2–130) | 38 (2–120) | 2 (2–13) | <0.00001 a |
| CRP (mg/l); median (range) | 3.7 (0.1–299) | 24.5 (0.67–342) | 0.3 (0.3–1.7) | <0.00001 a |
| fCal (µg/g); median (range) | 1789 (18.6–3405) | 1928 (522–3479) | 16 (3.8–64) | <0.00001 a |
UC: ulcerative colitis, CD: Crohn’s disease, Ctr: control group, PUCAI: pediatric ulcerative colitis activity index, PCDAI: pediatric Crohn’s disease activity index, NA: not applicable, No. of pts: number of patients, L1: distal 1/3 ileum, L2: colonic, L3: ileocolonic, B1: non-stricturing, non-penetrating, B2: stricturing, B2B3: stricturing, penetrating, G0: no evidence of growth delay, G1: growth delay, E1: ulcerative proctitis, E2: left-sided colitis, E3: extensive colitis (hepatic flexure distally), E4: pancolitis, SES-CD: simple endoscopic score for Crohn’s disease, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein, fCal: fecal calprotectin, NS: not significant, a UC vs. Ctr and CD vs. Ctr.