Figure 5.

Application of magnet controlled calcium alginate microspheres in drug release experiment in a model vessel. (a) Moving mechanism of the magnetic calcium alginate microsphere; (b)The increasing drug release rate promoted by the thermal response of calcium alginate microsphere; (c) Monodispersed microspheres with Fe₃O₄ nanoparticles; (d1) Microspheres with Fe₃O₄ nanoparticles sink in water; (d2) Microspheres with Fe₃O₄ nanoparticles could be attracted by a magnet; (e1–e8) Microspheres with Fe₃O₄ nanoparticles can be guided to move by the magnet in a capillary tube; (e9) The microspheres were treated by a hot water bag to promote drug release; (e10) Blue-O in the microspheres were released after hot compress treatment.