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editorial
. 2020 Jul 11;9(7):2193. doi: 10.3390/jcm9072193

Table 3.

Poor outcomes associated with fast tacrolimus metabolism (low C/D ratio).

Reported Poor Outcomes Associated with Fast Tacrolimus Metabolism (Low C/D Ratio)

  • Reduced allograft graft function

  • Allograft rejection

  • CNI nephrotoxicity

  • Faster decline in kidney function

  • Reduced death-censored graft survival

  • Dyslipidemia

  • Hypertension

  • Cardiovascular events

  • Post-transplant lymphoproliferative disorders