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. 2020 Jul 3;9(7):2097. doi: 10.3390/jcm9072097

Table 2.

Evolution of organ involvement among the 30 patients who presented an active sarcoidosis in adulthood.

First Presentation * Adulthood ** p
Organ involvement, median, (Q1–Q3) 4 (2.7–4) 1.5 (1–2) <0.0001 1
  Lung, n (%) 27 (90%) 14 (47%) 0.0006 2
  Eye, n (%) 15 (50%) 11 (36.6%) ns 2
  Kidney, n (%) 4 (13.3%) 2 (6.6%) ns 2
  Liver, n (%) 17 (56.3%) 7 (23.3%) 0.017 2
  Peripheral lymph node, n (%) 13 (43%) 3 (10%) 0.007 2
  Joints, n (%) 5 (17%) 1 (3.3%) ns 2
  Skin, n (%) 5 (17%) 3 (10%) ns 2
  Spleen, n (%) 6 (20%) 1 (3.3%) ns 2
  Central neurologic, n (%) 3 (10%) 3(10%) ns 2
General signs, n (%) 11 (36.7%) 2 (6.6%) <0.05 2
  Fever, n (%) 8 (26%) 0 (0%) 0.01 2
  Fatigue, n (%) 11 (36%) 2 (6.6%) <0.002 2

* Assessment of organ involvement at the first pediatric evaluation. Q1: first quartile, Q3: third quartile. ** Assessment of organ involvement in adulthood defined as a relapse after the age of 18. 1: p value obtained by Wilcoxon matched pairs signed rank test, 2: p value obtained by Fisher’s exact test. ns: nonsignificant.