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. 2020 Jul 11;12(7):1874. doi: 10.3390/cancers12071874

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cost-effectiveness results for each intervention in comparison to no intervention. EB: endometrial biopsy; GS: genetic screening + EB, TVS (plus colonoscopy to early detect colorectal cancer); HBS: hypothetical biomarker panel screening including prolactin (sensitivity and specificity of 0.98, both); IUD: Levonorgestrel intrauterine device; LR: lifetime risk; OCPs: oral contraceptive pills; PBSO: prophylactic bilateral salpingo-oophorectomy; PH: prophylactic hysterectomy; TVS: transvaginal sonography. § associated with Lynch syndrome. * Including risk-reducing surgery (e.g., hysterectomy, PBSO, polypectomy to prevent colorectal cancer) in mutation carrier.