Table 1.

Patient characteristics in the total population, group with and group without parametrial involvement in early stage cervical cancer.

Predictive Variable	Total Population n = 211		Group without Parametrial Invasion n = 200		Group with Parametrial Invasion n = 11		p
	n or Mean ± SD	(%) or (Range)	n or Mean ± SD	(%) or (Range)	n or Mean ± SD	(%) or (Range)
Age (years)
Mean ± SD	43.2 ± 11.6	(22–85)	43.1 ± 11.6	(22–85)	45.4 ± 12.4	(31–77)	0.52
<50	165	78.2	156	78	9	81.8	0.42
50–70	39	18.5	38	19	1	9.1
>70	7	3.3	6	3	1	9.1
BMI (kg/m2)
Mean ± SD	23.5 ± 5.1	(14.6–42.2)	23.3 ± 4.9	(14.6–41.4)	27.1 ± 7.8	(18–42.2)	0.02
<18.5	18	8.5	17	8.5	1	9.1	0.43
18.5–25	139	65.9	133	66.5	6	54.5
<25–30	29	13.7	28	14.0	1	9.1
>30	25	11.8	22	11.0	3	27.3
Parity
0	50	23.7	48	24.0	2	18.2	0.66
≥1	161	76.3	152	76.0	9	81.8
Menopausal status
Yes	52	24.6	49	24.5	3	27.3	0.83
No	159	75.4	151	75.5	8	72.7
Clinical FIGO stage
IA1 with emboli-IA2	24	11.5	24	12.1	0	0.0	0.63
IB1	115	55.0	108	54.5	7	63.6
IB2	67	32.1	63	31.8	4	36.4
IIA1	3	1.4	3	1.5	0	0.0
Not specified	2		2
Histology
Squamous cell carcinoma	142	67.6	132	67.9	10	90.9	0.23
Adenocarcinoma	61	29.0	60	29.6	1	9.1
Other type	7	3.3	7	2.6	0	0.0
Not specified	1		1
Grade of differentiation
G1	65	43.3	63	44.7	2	22.2	0.41
G2	58	38.7	53	37.6	5	55.6
G3	27	18.0	25	17.7	2	22.2
Not specified	61		59		2	2
Type of surgery
Radical Hysterectomy	160	75.8	150	75.0	10	90.9	0.23
Radical Trachelectomy	51	24.2	50	25.0	1	9.1
Type of Lymph node staging
SLN biopsy alone	65	30.8	64	32.0	1	9.1	0.11
SLN biopsy + Pelvic lymphadenectomy	146	69.2	136	68.0	10	90.9
Node status
Patients with positive SLN
Yes	29	13.7	23	11.5	6	54.5	<0.0001
No	182	86.3	177	88.5	5	45.5
SLN status
Macrometastasis	8	3.8	5	2.5	3	27.3	<0.0001
Micrometastasis	10	4.7	9	4.5	1	9.1
ITC	11	5.2	9	4.5	2	18.2
Negative	182	86.3	177	88.5	5	45.5
Final pathological exam
Tumor size
Mean (mm) ± SD	10 ± 11.9	(0–60)	9 ± 11.1	(0–60)	28.5 ± 10.9	(15–50)	<0.0001
<20 mm	158	76.7	156	80	2	18.2	<0.0001
≥20 mm	48	23.3	39	20	9	81.8
Not specified	5		5
Deep stromal invasion
Mean (mm) ± SD	5.6 ± 7.7	(0–40)	4.3 ± 7.8	(0–40)	17.6 ± 8.3	(6–30)	<0.0001
<10 mm	136	75.1	134	78.4	2	20.0	<0.0001
≥10 mm	45	24.9	37	21.6	8	80.0
Not specified	30		29		1
Lympho-vascular space invasion
Yes	71	33.6	62	31.0	9	81.8	0.001
No	140	66.4	138	69.0	2	18.2
Vaginal invasion
Yes	11	5.3	5	2.5	6	54.5	<0.0001
No	198	94.7	193	97.5	5	45.5
Not specified	2		2
Positive margin
Yes	10	4.8	6	3.0	4	36.4	<0.0001
No	199	95.2	192	97.0	7	63.6
Not specified	2		2

BMI, body mass index; SLN, sentinel lymph node; ITC, isolated tumor cells, SD standard deviation.