Table 1.
Age, sex, number of families/isolated cases of patients with suspected thyroid hormone (RTH) variants.
| ALL | RTHβ | FDH | Non-FDH/RTHβ | Not Available | |
|---|---|---|---|---|---|
| Age (years) | 32.3 ± 20.9 | 29.4 ± 21.2 | 28.5 ± 21.5 | 37.9 ± 19.2 | 37.8 ± 12.6. |
| Males (%) | 39 | 43 | 48 | 33 | 22 |
| Index cases | 303 | 115 | 29 | 136 | 23 |
| Next of kin | 91 | 79 | 4 | 8 | 0 |
ALL (all patients referred to our center); RTHβ (resistance to thyroid hormone with THRB variant); FDH (Familial Dysalbuminemic Hyperthyroxinemia with ALB variant); non-FDH/RTHβ (patient with no THRB or ALB variant); not available (no DNA for ALB molecular analysis); Next of kin: family members related to index cases.