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. 2020 Jul 7;9(7):2141. doi: 10.3390/jcm9072141

Table 2.

Previously published cases of isolated abdominal/retroperitoneal nocardiosis.

Case n°/Reference Year ** Age Sex Species Site Immune Status Therapy Regimen Therapy Duration Outcome
1 [28] 1976 49 F NR Spleen abscess Immunocompetent Sulfisoxazole NR survived
2 [9] 1981 26 F N. asteroides Perirenal area * Post renal transplant Sulphatriad, fusidic acid NR survived
3 [10] 1983 11 F N. asteroides Liver and kidney abscesses Immunocompetent Surgical resection, Amk, TMP/SMX, Sulphadimidine 12 weeks survived
4 [11] 1986 76 M N. asteroides Pancreas abscess Immunocompetent Surgical resection, A/clav, Amk, Orn, TMP/SMX NR survived
5 [41] 1990 19 M N. brasiliensis Cholecystitis and Peritonitis AIDS NR 7 days died
6 [12] 1991 38 M N. asteroides Left suprarenal abscess AIDS Surgical resection NR died
7 [13] 1996 67 M N. asteroides Abdominal aortic aneurysm Immunocompetent TMP/SMX, Amk NR survived
8 [14] 2003 42 M N. farcinica Psoas abscess Immunocompetent TMP/SMX 11 months survived
9 [15] 2004 37 F NR Abdominal abscess M. Crohn NR NR NR
10 [5] 2004 34 M N. asteroides Left Adrenal abscess AIDS Surgical resection, TMP/SMX, Cef NR survived
11 [16] 2007 25 F NR Bilateral kidney abscesses Corticosteroids and Azathioprin for SLE Methylprednisolone NR died
12 [17] 2007 44 F NR Jejunum Post liver transplant Surgical resection, Imi, Van NR died
13 [18] 2009 55 M NR Kidney abscess AIDS Surgical resection NR NR
14 [42] 2010 83 F N. veterana Bowel abscess Colon cancer Surgical resection, Cef, Gen, Met, TMP/SMX NR survived
15 [19] 2011 32 F NR Bilateral abscesses of ovaries and fallopian tubes, omentum Immunocompetent Surgical resection, Mino, TMP/SMX, Amk, Line, Cip 6 Months survived
16 [20] 2012 59 F N. farcinica Right adrenal compartment Chronic hepatitis C,
post treatment for lymphoma
Amk, Cefu, TMP/SMX 4 months died
17 [21] 2012 54 F NR Colon Immunocompetent Surgical resection, antibiotics not specified NR survived
18 [22] 2013 30 F NR Left adnexal collection * Immunocompetent TMP/SMX, Amk 6 months survived
19 [24] 2016 58 F N. farcinica Colon, blood TNFa-antagonist for M. Crohn Van, Met, Imi, Amk, TMP/SMX 12 months survived
20 [23] 2017 59 M N. farcinica Liver abscess Post liver transplant TMP/SMX, Amk, Imi NR survived
21 [2] 2018 63 F N. paucivorans Renal abscess Post lung transplant Surgical resection, Imi, TMP/SMX 9–12 months NR
22 [25] 2019 63 M N. farcinica Liver (hepatitis) Immunocompetent TMP/SMX, Amk 4 weeks died
23 [26] 2019 11 F N. farcinica Abdominal abscesses Post renal transplant TMP/SMX, Mer, Imi, Cila, Line NR NR
24 [present report] 81 M N. paucivorans Right adrenal space B-Cell Lymphoma, Hypogammaglobulinemia Surgical resection, A/clav, TMP/SMX, Amk, Cef, Mino, Cip 6 months survived

Abbreviations: AIDS = acquired immunodeficiency syndrome; Amk = amikacin; A/clav = amoxicillin + clavulanic acid; Cef = ceftriaxone; Cefu = cefuroxime; Cila = cilastin; Cip = ciprofloxacin; Gen = gentamycin; Imi = imipenem; Line = linezolid; Mer = meropenem; Mino = minocycline; NR = not reported; Orn = ornidazole; SLE = systemic lupus erythematodes; TNFa = tumor necrosis factor alpha; TMP/SMX = trimethoprim-sulfamethoxazole; Van = vancomycin; * not further specified; ** Year of publication.