Table 2.
Characteristics of female and male patients with ACS between 2005 and 2015; see Tables S3 and S4 for results displayed by year.
| Females | Males | p-Value—2005 | p-Value—2015 | |||
|---|---|---|---|---|---|---|
| 2005 | 2015 | 2005 | 2015 | |||
| N available | 140,755 | 108,292 | 232,444 | 209,146 | <0.001 | <0.001 |
| Age (years) | 72.7 ± 11.9 | 73.2 ± 12.4 | 65.6 ± 12.2 | 67.0 ± 12.7 | <0.001 | <0.001 |
| Hypertension | 80,346 (57.1%) | 63,780 (58.9%) | 130,153 (56.0%) | 121,749 (58.2%) | <0.001 | 0.001 |
| Dyslipidemia | 50,992 (36.2%) | 45,576 (42.1%) | 100,662 (43.3%) | 101,255 (48.4%) | <0.001 | <0.001 |
| Diabetes | 40,858 (29.0%) | 32,068 (29.6%) | 53,755 (23.1%) | 57,241 (27.4%) | <0.001 | <0.001 |
| PAD | 4757 (3.4%) | 4929 (4.6%) | 11,218 (4.8%) | 12,365 (5.9%) | <0.001 | <0.001 |
| Prior stroke | 1656 (1.2%) | 964 (0.9%) | 1987 (0.9%) | 1506 (0.7%) | <0.001 | <0.001 |
| Atrial fibrillation | 24,353 (17.3%) | 22,832 (21.1%) | 30,371 (13.1%) | 36,826 (17.6%) | <0.001 | <0.001 |
| COPD | 8376 (6.0%) | 8087 (7.5%) | 16,840 (7.2%) | 15,910 (7.6%) | <0.001 | 0.371 |
| Renal insufficiency | 21,728 (15.4%) | 25,858 (23.9%) | 33,080 (14.2%) | 39,229 (18.8%) | <0.001 | <0.001 |
| Prior CABG | 5845 (4.2%) | 5186 (4.8%) | 18,183 (7.8%) | 17,347 (8.3%) | <0.001 | <0.001 |
| During hospital stay | ||||||
| Mean hospital-stay duration (days) | 8.4 ± 8.0 | 6.8 ± 7.0 | 7.4 ± 7.5 | 6.4 ± 6.9 | <0.001 | <0.001 |
| Coronary angiography | 63,248 (44.9%) | 69,879 (64.6%) | 132,468 (57.0%) | 153,857 (73.6%) | <0.001 | <0.001 |
| Inhospital PCI | 37,193 (26.4%) | 46,276 (42.7%) | 89,074 (38.3%) | 113,369 (54.2%) | <0.001 | <0.001 |
| Inhospital CABG | 4588 (3.3%) | 3336 (3.1%) | 13,115 (5.6%) | 11,547 (5.5%) | <0.001 | <0.001 |
| Inhospital mortality | 11,582 (8.2%) | 7766 (7.2%) | 12,450 (5.4%) | 11,064 (5.3%) | <0.001 | <0.001 |