Table 3.
Systemic comorbidities and dry eye parameters.
| No. of Cases | Schirmer Test (mm) (Mean ± SD) |
TBUT (s) (Mean ± SD) |
Keratoconjunctival Staining Score (Points) (Mean ± SD) |
DEQS (Mean ± SD) |
HUI (Mean ± SD) |
||
|---|---|---|---|---|---|---|---|
| Systemic comorbidity | + | 219 | 8.38 ± 8.20 | 2.49 ± 1.59 | 3.16 ± 1.86 | 25.15 ± 20.69 | 0.72 ± 0.23 |
| − | 230 | 10.98 ± 10.39 | 2.94 ± 1.51 | 2.47 ± 1.99 | 28.35 ± 20.50 | 0.79 ± 0.20 | |
| p-value | 0.004 * | 0.002 * | 0.0002 * | 0.104 | 0.003 * | ||
| Age-adjusted p-value | 0.656 | 0.011 * | <0.001 * | 0.411 | 0.030 * | ||
| Hypertension * | + | 108 | 7.61 ± 7.19 | 2.66 ± 1.65 | 2.96 ± 1.75 | 21.71 ± 18.68 | 0.73 ± 0.24 |
| − | 341 | 10.36 ± 9.99 | 2.74 ± 1.54 | 2.75 ± 2.02 | 28.40 ± 20.98 | 0.76 ± 0.21 | |
| p-value | 0.008 | 0.645 | 0.334 | 0.004 * | 0.275 | ||
| Age-adjusted p-value | 0.694 | 0.820 | 0.347 | 0.406 | 0.897 | ||
| Insomnia * | + | 67 | 8.63 ± 8.96 | 2.31 ± 1.55 | 2.81 ± 1.80 | 26.31 ± 19.59 | 0.74 ± 0.19 |
| − | 382 | 9.88 ± 9.53 | 2.80 ± 1.56 | 2.80 ± 1.99 | 26.87 ± 20.83 | 0.76 ± 0.22 | |
| p-value | 0.318 | 0.018 | 0.993 | 0.84 | 0.516 | ||
| Age-adjusted p-value | 0.698 | 0.044 * | 0.960 | 0.249 | 0.938 | ||
| Depression * | + | 20 | 5.50 ± 5.85 | 2.03 ± 1.84 | 2.15 ± 1.90 | 26.05 ± 18.05 | 0.725 ± 0.213 |
| − | 429 | 9.89 ± 9.54 | 2.76 ± 1.55 | 2.83 ± 1.96 | 26.82 ± 20.76 | 0.756 ± 0.215 | |
| p-value | 0.042 * | 0.043 * | 0.127 | 0.874 | 0.55 | ||
| Age-adjusted p-value | 0.056 | 0.049 * | 0.125 | 0.993 | 0.598 | ||
TBUT, tear film break up time; DEQS, Dry Eye-Related Quality-of-Life Score; HUI, health utilities index; * p ≤ 0.05; “+”: presence; “−”: absence.