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. 2020 Jun 29;9(7):2040. doi: 10.3390/jcm9072040

Table 4.

Oral medicine and dry eye parameters.

No. of Cases Schirmer Value (mm) TBUT (s) Fluorescein Staining Score DEQS HUI
Antihypertensive (+) 98 7.50 ± 6.84 2.74 ± 1.68 2.92 ± 1.73 21.39 ± 18.95 0.73 ± 0.25
(−) 351 10.31 ± 9.99 2.72 ± 1.53 2.77 ± 2.02 28.33 ± 20.86 0.76 ± 0.20
p 0.009 * 0.901 0.514 0.003 * 0.272
Age-adjusted 0.626 0.413 0.548 0.342 0.853
Sedative (+) 55 8.64 ± 9.13 2.38 ± 1.61 2.93 ± 1.82 27.54 ± 20.16 0.74 ± 0.20
(−) 394 9.84 ± 9.49 2.77 ± 1.55 2.79 ± 1.98 26.69 ± 20.72 0.76 ± 0.22
p 0.378 0.078 0.619 0.779 0.485
Age-adjusted 0.741 0.149 0.649 0.138 0.837
Antidepressant (+) 20 5.50 ± 5.85 2.03 ± 1.84 2.15 ± 1.90 26.05 ± 18.05 0.73 ± 0.21
(−) 429 9.89 ± 9.54 2.76 ± 1.55 2.83 ± 1.96 26.82 ± 20.76 0.76 ± 0.22
p 0.042 * 0.043 * 0.127 0.874 0.55
Age-adjusted 0.056 0.049 * 0.125 0.993 0.598

TBUT: tear film break up time; DEQS: Dry Eye-Related Quality-of-Life Score; HUI: Health Utilities Index. * p < 0.05. Mean ± SD; “+”: presence; “−”: absence.