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. 2020 Jun 29;9(7):2040. doi: 10.3390/jcm9072040

Table 5.

Association between dry eye subtype and systemic comorbidities.

DE Subtype (ADDE/sTBUT)
OR (95% Cl) p Value Adjusted OR (95% CI) p Value
Hypertension 1.46 (0.82–2.58) 0.20 1.17 (0.64–2.15) 0.61
Insomnia 0.97 (0.51–1.81) 0.92 0.80 (0.41–1.53) 0.49
Depression 1.69 (0.54–5.27) 0.36 1.67 (0.53–5.22) 0.38
MGD (Yes/No)
OR (95% CI) p Value Adjusted OR 95% CI) p Value
Hypertension 2.65 (1.64–4.28) <0.01 1.33 (0.78–2.27) 0.30
Insomnia 1.94 (1.10–3.42) 0.02 1.21 (0.66–2.21) 0.54
Depression 0.38 (0.09–1.67) 0.20 0.33 (0.07–1.49) 0.15
FRD (Yes/No)
OR (95% CI) p Value Adjusted OR (95% CI) p Value
Hypertension 1.56 (1.00–2.44) 0.05 1.10 (0.68–1.79) 0.70
Insomnia 2.66 (1.57–4.51) <0.01 2.16 (1.26–3.72) <0.01
Depression 4.92 (1.85–13.08) <0.01 4.89 (1.81–13.22) <0.01

OR, odds ratio; CI, confidence Interval; ADDE, aqueous-deficient dry eye; DE, dry eye; sTBUT, short tear film break up time dry eye; MGD, meibomian gland dysfunction; FRD, friction-related disease.