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Sequential drug screens show new candidates for sickle-cell disease (SCD). (A) Workflow procedure for performing in-cell Western experiment. Further details are available in the methods section; (B) sample layout and result for screen of NIH Clinical Collection on K562 cells. Fetal hemoglobin signal normalized to DMSO treated cells; (C) signal-to-cell ratios for drug duplicates by plate on K562 cells.
