Figure 1.

Study design overview. Eighteen participants completed a six-week resistance exercise training intervention followed by eight weeks of deconditioning (detraining—no exercise). Muscle strength was evaluated by a three-repetition max test before and after resistance exercise training. Skeletal muscle biopsies were taken from the vastus lateralis muscle on each test day. Furthermore, a biopsy was taken after two, four, and six weeks of deconditioning.