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. 2020 Jul 20;9(7):1733. doi: 10.3390/cells9071733

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Patient-specific (patho-)physiological features mirrored by cardiac organoids. (A–C) Analysis of the beating patterns and rates of Cor-Oids, WTS-Oids and UKK-Oids on day 21 (A) Cor-Oids showed a regular beating pattern with a beating rate of 82 ± 2 bpm (B) WTS-Oids showed a similar regular beating pattern, but a slower beating rate than Cor-Oids (C) UKK-Oids presented an arrhythmic beating pattern and a significant variability in their beating rate. RFI = Relative Fluorescence Intensity.