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. 2020 Jul 16;12(7):1922. doi: 10.3390/cancers12071922

Figure 5.

Figure 5

CN133 is more potent than SAHA in increasing histone acetylation in vivo: Western Blot of spleen (a) or brain tumors (b) from mice treated for 14 days with 5 mg/kg C133 or 50 mg/kg SAHA administered twice a day by i.p. Numbers above the western blots indicate mouse identification. Uncropped Blots of Figure 5a,b are shown in Figure S9 (c,d) Densitometry analysis of H2BK5ac levels normalized to H3. Fold changes are relative to values from vehicle-injected mice. ** p < 0.01; *** p < 0.001.