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. 2020 Jul 15;12(7):1909. doi: 10.3390/cancers12071909

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Differential expression analysis of EZR-negative tumor cells. Volcano plot of TOP 10 up- and downregulated genes (A). TOP 10 KEGG signaling pathways and GO biological processes (B). Up- and downregulated genes with an unadjusted p-value < 0.05 were used for functional enrichment analysis. The left panel shows –log10p of the perturbation determined from a gene set test, whereas the right panel demonstrates a percentage of genes from corresponding KEGG and GO nodes that are down- and upregulated.