List of Abbreviations:	Full Name:
α-SMA	α- smooth muscle actin
ADT	Androgen-deprivation therapy
AR	Androgen Receptor
ASPN	Asporin
BCR	Biochemical recurrence
BM	Bone metastasis
BMPs	Bone morphogenetic proteins
BPH	Benign prostatic hyperplasia
CAFs	Cancer-associated fibroblasts
CD	Cluster of designation antigens
CRPC	Castration-resistant prostate cancer
CXCL	Chemokine (C-X-C motif) ligand
CXCR	Chemokine (C-X-C motif) receptor
ECM	Extracellular matrix
EMT	Epithelial to mesenchymal transition
EVs	Extracellular vesicles
FAP	Fibroblast activation protein
FGFs	Fibroblast growth factors
FSP-1 (also known as S100A4)	Fibroblast-specific protein-1
GDF15	Growth differentiation factor 15
HGF	Hepatocyte growth factor
HSCs	Hematopoietic stem cells
IGFs	Insulin-like growth factors
ILs	Interleukins
MFBs	Myofibroblasts
MMPs	Matrix metalloproteinases
OB-BMST	Osteoblastic bone metastasis-associated stroma transcriptome
PCa	Prostate cancer
PDGFR	Platelet-derived growth factor receptor
PIA	Proliferative inflammatory atrophy
PIN	Prostatic intraepithelial neoplasia
POSTN	Periostin
PSA	Prostate-specific antigen
ROS	Reactive-oxygen species
TGF-β	Transforming growth factor -β
TGFβRII	TGF-β receptor type II
TIMPs	Tissue inhibitors of matrix metalloproteinases
TME	Tumor microenvironment
TNC	Tenascin C
VEGF	Vascular endothelial growth factor