Table 1.
Hyaluronan secretion levels and average length and density of filopodia in different cell lines producing various levels of hyaluronan endogenously, or via different manipulations.
| Cell Line | Hyaluronan Secretion (ng/10,000 cells/24 h) | Average Density of Filopodia (U/µm) | Average Length of Filopodia (µm) |
|---|---|---|---|
| MCF-7-HAS3 Dox- | 0.11 | 0.18 | 0.82 |
| MCF-7-HAS3 0 mM Glc | 2.30 | 0.20 | 0.90 |
| MCF-7-HAS3 2 mM Glc | 4.84 | 0.21 | 0.91 |
| MCF-7-HAS3 5 mM Glc | 5.23 | 0.22 | 0.95 |
| MCF-7-HAS3 10 mM Glc | 4.69 | 0.25 | 0.98 |
| MCF-7-HAS3 + GlcN | 19.0 | 0.18 | 1.10 |
| MCF-7-HAS3 + Man | 1.41 | 0.14 | 0.70 |
| MCF-7-HAS3 + 4-MU | 2.70 | 0.19 | 0.84 |
| MKN74 MOCK | 2.50 | 0.25 | 0.80 |
| MKN74 CD44 | 1.90 | 0.24 | 0.90 |
| MCF10A | 0.19 | 0.45 | 1.99 |
| MCF10A + GlcN | 0.40 | 0.45 | 2.16 |
| MCF10A + Man | 0.07 | 0.37 | 1.92 |
| MCF10A + 4-MU | 0.18 | 0.31 | 1.22 |
| MCF10CA | 1.84 | 0.50 | 2.64 |
| MCF10CA + GlcN | 3.81 | 0.54 | 2.62 |
| MCF10CA + Man | 0.24 | 0.19 | 1.40 |
| MCF10CA + 4-MU | 1.46 | 0.25 | 1.14 |