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. 2020 Jul 20;12(7):1969. doi: 10.3390/cancers12071969

Figure 5.

Figure 5

Engineering expression of IL-7 enhances the antitumor activity of NKG2D-CAR T cells in the xenograft prostate tumor model. (a) A schematic of in vivo experiment. (b) Kaplan-Meier survival analysis of PC-3 challenged mice after treatment with CAR-T cells. (c,d) The photograph of residual tumors (c) and the tumor weight (d) of the mice treated with NKG2D-CAR and NKG2DIL7-CAR T cells at the endpoint of the experiments. * p < 0.05, *** p < 0.001, **** p < 0.0001, n = 6.