Table 5.
Survival outcomes of Child–Pugh B patients.
| Entire Cohort | ||||||
|---|---|---|---|---|---|---|
| Outcome | Median Time, Week (95% CI) |
Univariate Analysis | Multivariable Analysis | |||
| Child–Pugh B7 (n = 41) |
Child–Pugh B8/9 (n = 30) |
HR (95% CI) a |
p Value | AHR (95% CI) a |
p Value | |
| Overall survival | 15.3 (9.3–22.3) |
7.4 (6.4–14.9) |
1.64 (0.98–2.72) |
0.058 | 1.93 (1.11–3.35) |
0.020 |
| Progression-free survival | 6.3 (5.0–8.0) |
4.8(3.7–7.6) | 1.23 (0.74–2.04) |
0.416 | 1.53 (0.86–2.58) |
0.153 |
| Time to progression | 6.9 (6.0–12.6) |
6.1 (4.6–NA) |
1.04 (0.57–1.88) |
0.895 | 1.30 (0.70–2.40) |
0.408 |
a Cox proportional hazard regression model for the Child–Pugh B8/9 group with the Child–Pugh B7 group as a reference. Abbreviations: AHR, adjusted hazard ratio; CI, confidence interval; HR, hazard ratio; NA, not applicable.