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Adverse events requiring discontinuation or dose delay.
| Adverse Events | Child–Pugh A (n = 132) |
Child–Pugh B (n = 71) |
||
|---|---|---|---|---|
| Any Grade | Grade ≥ 3 | Any Grade | Grade ≥ 3 | |
| Hepatitis | 3 (2.3) | 2 (1.5) | 3 (4.2) | |
| Pneumonitis | 3 (2.3) | 3 (2.3) | ||
| Anorexia | 3 (2.3) | 6 (8.5) | 1 (1.4) | |
| Nausea | 1 (0.8) | 1 (1.4) | ||
| Pain | 1 (0.8) | 3 (4.2) | ||
| Anemia | 3 (2.3) | 3 (4.2) | ||
| Fatigue | 1 (0.8) | 5 (7.0) | ||
| Rash | 2 (1.5) | 1 (1.4) | ||
| Insomnia | 1 (1.4) | |||
