TAM |
tumor-associated macrophages |
CCL2 |
C-C motif chemokine ligand 2 |
CSF |
colony-stimulating factor |
PD-1 |
programmed cell death 1 |
OV |
oncolytic virus |
TLR |
toll-like receptors |
LPS |
lipopolysaccharide |
TGFβ |
transforming growth factor β |
PGE2 |
prostaglandin E, |
Arg 1 |
arginase 1 |
MMR |
macrophage mannose receptor |
IFN |
interferon |
IL |
interleukin |
TNFα |
tumor necrosis factor alpha |
MHC II |
class of major histocompatibility complex |
iNOS |
inducible nitric oxide synthase |
pSTAT |
phosphorylated signal transducer and activator of transcription |
MGL |
macrophage galactose-type lectin |
VEGF |
vascular endothelial growth factor |
EGF |
epidermal growth factor |
FGF |
fibroblast growth factors |
uPA |
urokinase plasminogen activator |
TP |
thymidine phosphorylase |
ADM |
adrenomedullin, |
Sema4D |
semaforin 4D |
MMPs |
metalloproteinases |
CCL 3,4,5, 22 |
C-C motif chemokine ligand 3,4,5,22 |
CSF1R |
CSF1 receptor |
FDA |
Food and Drug Administration |
M2pep |
macrophage-targeting peptide |
CCL |
C-C motif chemokine ligand |
CCR |
C-C motif chemokine receptor |
HIV1 |
human immunodeficiency virus 1 |
CXCL |
C–X–C motif chemokine ligand |
NK |
natural killer |
CXCR |
C-X-C motif chemokine receptor |
GM-CSF |
granulocyte-macrophage colony-stimulating factor |
Ang-2 |
Angiopoietin 2 |
SIRPα |
signal-regulatory protein α |
MARCO |
macrophage receptor with collagenous structure |
CTLA4 |
cytotoxic T-lymphocytes antigen 4 |
PI3Kγ |
phosphoinositide 3 kinase γ |
STAT1 |
signal transducer and activator of transcription 1 |
CAR-T |
chimeric antigen receptor T cell therapies |
STING |
stimulator of interferon genes |
COX |
cyclooxygenase-2 |
DCs |
dendritic cells |
CTLs |
cytotoxic T lymphocytes |
5-FU |
5-fluorouracile |
Gy |
gray |
NO |
nitric oxide |
HLA-DR |
human leukocyte antigen-cell surface receptor |
IRF |
interferon-regulatory factor |
ATM |
ataxia telangiectasia mutated |
ICB |
immune check point blocking |
PD-L1-2 |
programmed death ligand 1-2 |
VISTA |
V-domain immunoglobulin suppressor of T cell activation |
CD40L |
ligand of the CD40 receptor |
GCP-2 |
granulocyte chemotactic protein 2 |
MIP-1 |
macrophage inflammatory protein -1 |
MCP 1,3,5 |
monocyte chemoattractant protein 1,3,5 |
CCN1 |
cellular communication network factor1 |
mesoCA T cell |
mesothelin-redirected chimeric antigen receptor T cell |