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. 2020 Jul 21;12(7):1987. doi: 10.3390/cancers12071987
TAM tumor-associated macrophages
CCL2 C-C motif chemokine ligand 2
CSF colony-stimulating factor
PD-1 programmed cell death 1
OV oncolytic virus
TLR toll-like receptors
LPS lipopolysaccharide
TGFβ transforming growth factor β
PGE2 prostaglandin E,
Arg 1 arginase 1
MMR macrophage mannose receptor
IFN interferon
IL interleukin
TNFα tumor necrosis factor alpha
MHC II class of major histocompatibility complex
iNOS inducible nitric oxide synthase
pSTAT phosphorylated signal transducer and activator of transcription
MGL macrophage galactose-type lectin
VEGF vascular endothelial growth factor
EGF epidermal growth factor
FGF fibroblast growth factors
uPA urokinase plasminogen activator
TP thymidine phosphorylase
ADM adrenomedullin,
Sema4D semaforin 4D
MMPs metalloproteinases
CCL 3,4,5, 22 C-C motif chemokine ligand 3,4,5,22
CSF1R CSF1 receptor
FDA Food and Drug Administration
M2pep macrophage-targeting peptide
CCL C-C motif chemokine ligand
CCR C-C motif chemokine receptor
HIV1 human immunodeficiency virus 1
CXCL C–X–C motif chemokine ligand
NK natural killer
CXCR C-X-C motif chemokine receptor
GM-CSF granulocyte-macrophage colony-stimulating factor
Ang-2 Angiopoietin 2
SIRPα signal-regulatory protein α
MARCO macrophage receptor with collagenous structure
CTLA4 cytotoxic T-lymphocytes antigen 4
PI3Kγ phosphoinositide 3 kinase γ
STAT1 signal transducer and activator of transcription 1
CAR-T chimeric antigen receptor T cell therapies
STING stimulator of interferon genes
COX cyclooxygenase-2
DCs dendritic cells
CTLs cytotoxic T lymphocytes
5-FU 5-fluorouracile
Gy gray
NO nitric oxide
HLA-DR human leukocyte antigen-cell surface receptor
IRF interferon-regulatory factor
ATM ataxia telangiectasia mutated
ICB immune check point blocking
PD-L1-2 programmed death ligand 1-2
VISTA V-domain immunoglobulin suppressor of T cell activation
CD40L ligand of the CD40 receptor
GCP-2 granulocyte chemotactic protein 2
MIP-1 macrophage inflammatory protein -1
MCP 1,3,5 monocyte chemoattractant protein 1,3,5
CCN1 cellular communication network factor1
mesoCA T cell mesothelin-redirected chimeric antigen receptor T cell