Table 5.
Optimization results of Geobacillus icigianus model for 2,3-butanediol production with the pFBA algorithm.
| Substrate | Production of 2,3-Butanediol (mmol gDCW−1 h−1) |
Growth Rate (h−1) |
Reaction Modifications * |
|---|---|---|---|
| Glucose | 4.16 | 0.42 | EX_o2_e = 0.03125 |
| Arabinose | 4.11 | 0.41 | O2t = 0.03125 |
| Xylose | 4.12 | 0.41 | O2t = 0.03125 |
| FE3abc = 0.03125 | |||
| Xylose | 4.11 | 0.41 | O2t = 0.03125 |
| Glycerine | 12.23 | 0.25 | O2t = 0.0625 |
* Value less than 1—a decrease in the flux value through the reaction compared to wildtype. A value greater than 1 is an increase in the flux value through the reaction compared to the wildtype. O2t—oxygen transport from the extracellular space into the cell; EX_o2_e—exchange reaction for oxygen; FE3abc—ATP phosphohydrolase (iron ion transport).