Scheme 3. Reagents and conditions:
(a) N-(4-bromophenyl)-2-chloroacetamide, K2CO3, anhydrous CH3CN, reflux, 2–6 h; (b) Br2, glacial CH3COOH, r.t. 90 min; (c) 3-methoxyphenylboronic acid, tetrakis, anhydrous toluene, 2N Na2CO3, 80 °C, 4–7 h.
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