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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Bioorg Chem. 2020 Apr 28;100:103880. doi: 10.1016/j.bioorg.2020.103880

Table 3.

Effect of selected compounds on human neutrophil chemotaxis

Compound Chemotaxis
EC50 (μM) IC50 (μM)a
2a 0.02 ± 0.004 6.1 ± 1.1
2c 0.06 ± 0.015 18.8 ± 3.2
2d 0.013 ± 0.001 8.4 ± 1.2
17bb 0.6 ± 0.4b 5.2 ± 1.6
graphic file with name nihms-1614142-t0009.jpg
a

Desensitization of human neutrophil chemotaxis toward WKYMVm.

b

As reported previously [26].