Table 2.

19 potential activity compounds of Evodia rutaecarpa

Number	Molecule name	OB (%)	BBB	DL
1	Evodiamine	86.02	0.85	0.64
2	Goshuyuamide I	83.19	0.64	0.39
3	Evodiamide	73.77	0.81	0.28
4	N-(2-methylaminobenzoyl) tryptamine	56.96	0.8	0.26
5	Fordimine	55.11	0.75	0.26
6	Evocarpine	48.66	1.17	0.36
7	1-Methyl-2-[(Z)-undec-6-enyl]-4-quinolone	48.48	1.14	0.27
8	1-Methyl-2-[(Z)-pentadec-10-enyl]-4-quinolone	48.45	1.11	0.46
9	1-Methyl-2-nonyl-4-quinolone	48.42	1.21	0.2
10	1-Methyl-2-undecyl-4-quinolone	47.59	1.19	0.27
11	Icosa-11,14,17-trienoic acid methyl ester	44.81	1.07	0.23
12	1-Methyl-2-pentadecyl-4-quinolone	44.52	1.05	0.46
13	Dihydrorutaecarpine	42.27	0.7	0.6
14	Rutaecarpine	40.3	0.71	0.6
15	24-Methyl-31-norlanost-9(11)-enol	38	1	0.75
16	Beta-sitosterol	36.91	0.99	0.75
17	Sitosterol	36.91	0.87	0.75
18	Berberine	36.86	0.57	0.78
19	1-(5,7,8-Trimethoxy-2,2-dimethylchromen-6-yl) ethanone	30.39	0.75	0.18

OB oral bioavailability, DL drug-likeness, BBB blood–brain barrier