Table 1.
Baseline characteristics of all subjects in the discovery and verification phases
| Discovery phase | Verification phase | |||||
|---|---|---|---|---|---|---|
|
|
|
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| AMI (n = 10) mean (SD) | Control (n = 10) mean (SD) | P-value | AMI (n = 40) mean (SD) | Control (n = 80) mean (SD) | P-value | |
| Age, years | 39.7 (3.7) | 38.2 (3.7) | 0.380 | 37.8 (5.5) | 33.0 (6.2) | < 0.001 |
| BMI, kg/m2 | 25.33 (3.36) | 24.99 (5.31) | 0.712 | 29.62 (6.88) | 26.26 (4.70) | 0.002 |
| Current smoker, n (%) | 10 (100%) | 10 (100%) | - | 33 (82.5%) | 27 (33.8%) | < 0.001 |
| Smoking pack, years* | 20.0 (9.5) | 4.8 (8.7) | 0.003 | 16.0 (13.8) | 4.8 (3.8) | < 0.001 |
| SBP, mmHg | 127.8 (19.4) | 114.2 (3.2) | 0.056 | 134.9 (19.6) | 121.6 (10.1) | < 0.001 |
| DBP, mmHg | 84.1 (13.0) | 71.6 (4.4) | 0.010 | 87.7 (14.8) | 78.5 (7.5) | < 0.001 |
| Fasting glucose, mmol/L* | 6.19 (0.48) | 5.48 (0.47) | <0.001 | 6.30 (1.11) | 4.90 (0.50) | < 0.001 |
| Total cholesterol, mmol/L | 5.33 (1.61) | 6.25 (1.10) | 0.146 | 5.63 (1.56) | 5.95 (1.09) | 0.235 |
Notes: Values are presented as means (SD);
*
median (IQR) or numbers; (%); data was analysed using independent Student’s t-test for normally distributed data;
*
Mann Whitney U test for not normally distributed data and Chi squared test for categorical data;
BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; AMI = acute myocardial infarction