Table 2.

Baseline radiomics features of primary tumours – Mann-Whitney U-test (MWU) and receiver operating characteristic (ROC) curve analysis. Patients were dichotomized into 2 groups: responders (OS > 14.9 months) and non-responders (OS < 14.9 months). For each radiomics feature median value, range, p-value of MWU, and the area under the ROC curve (AUC) with the corresponding 95% confidence interval (CI), are reported. See also Figure 1

Feature	Responders (OS > 14.9 months) median (range)	Non-responders (OS < 14.9 months) median (range)	p-value	AUC (95% CI)
Volume [cm3]	27.9 (2.64–351)	44.4 (7.81–792)	0.098	0.69 (0.49–0.89)
SUVmax [g/ml]	20.6 (5.21–32.1)	15.6 (9.54–37.0)	0.185	0.65 (0.43–0.87)
Sum entropy	3.69 (3.53–3.77)	3.7 (3.54–3.76)	0.387	0.60 (0.38–0.82)
Entropy-GLCM	4.07 (3.99–4.15)	4.11 (4.03–4.14)	0.046	0.72 (0.52–0.92)
Difference entropy	2.98 (2.74–3.07)	2.89 (2.74–3.06)	0.080	0.70 (0.49–0.90)
Small Run Emphasis (SRE)	0.0382 (0.00962–0.0615)	0.0163 (0.00854–0.0303)	0.001	0.85 (0.69–1.00)

GLCM = Grey-Level Co-occurrence Matrix; SUV_max = maximum standardized uptake value