Fig. 4.

Distribution of genetic changes in several receptor tyrosine kinase genes of the patients with LUSC and PDX models. WES is the source for the somatic mutations of the genes and WTS for the DEGs. The yellow box indicates shared somatic mutations in the patients with LUSC and PDX models; the red box indicates upregulated genes in both the patients with LUSC and PDX models; and the blue box indicates downregulated genes in both the patients with LUSC and PDX models. The number represents the frequency of somatic mutations or fold changes of the gene