Table 1.
Clinical and laboratory data by group
| AIS (n = 35) | AIS + D (n = 8) | χ2 | p | |
|---|---|---|---|---|
| Age | 64.5 ± 14.1 | 85.8 ± 9.6 | 0.0003 | |
| Sex | 0.73 | 0.39 | ||
| Male | 27 (77%) | 5 (63%) | ||
| Female | 8 (23%) | 3 (37%) | ||
| Time from stroke onset to venipuncture (h) | 44.4 ± 17.5 | 39.5 ± 20.9 | 0.53 | |
| Initial NIHSS | 4.3 ± 4.3 | 11.9 ± 8.1 | 0.009 | |
| Other conditions | ||||
| Atrial arrhythmia | 7 (20%) | 6 (75%) | 9.34 | 0.002 |
| Kidney disease | 4 (11%) | 0 (0%) | 1.01 | 0.32 |
| Hyperlipidemia | 21 (60%) | 4 (50%) | 0.27 | 0.61 |
| Heart failure | 3 (9%) | 4 (50%) | 8.20 | 0.004 |
| Diabetes | 7 (20%) | 1 (3%) | 0.24 | 0.62 |
| Coronary artery disease | 5 (14%) | 1 (13%) | 0.02 | 0.90 |
| Obesity | 2 (6%) | 0 (0%) | 0.48 | 0.49 |
| Hypothyroidism | 3 (9%) | 0 (0%) | 0.74 | 0.39 |
| Smoking / COPD | 6 (17%) | 2 (25%) | 0.27 | 0.61 |
| Gastritis / ulcer | 4 (11%) | 0 (0%) | 1.01 | 0.32 |
| Parkinson’s disease | 0 (0%) | 1 (13%) | 4.48 | 0.03 |
| IL-6 (pg/mL) | 0 (0–5.5) | 11.5 (9.8–18.0) | 0.002 | |
| CRP (mg/L) | 3.5 (1.6–9.6) | 19.8 (13.2–41.8) | 0.003 | |
| S100B (ng/L) | 55.0 (46.0–91.5) | 94.5 (71.8–464) | 0.065 | |
| CC3 (mg/dL) | 130 (111–142) | 111 (105–123) | 0.16 | |
Note: Age is presented as mean ± standard deviation. Laboratory values are presented as median and range between 25th percentile and 75th percentile values, with between group comparisons performed using the Mann-Whitney U test