Table 2.

Exploratory analysis comparing the AIS + D group to a subgroup of AIS patients with similarly severe strokes

	AIS + D (n = 8)	mild AIS (n = 29)	p	severe AIS (n = 6)	p
IL-6 (pg/mL)	11.5 (9.8–18.0)	0 (0–6.0)	0.009	0 (0–0)	0.012
CRP (mg/L)	19.8 (13.2–41.8)	3.0 (1.0–10.0)	0.004	4.3 (3.6–5.0)	0.033

Note: Laboratory values are presented as median and range between 25th percentile and 75th percentile values, with between group comparisons between AIS + D and mild AIS or severe AIS controls performed using the Mann-Whitney U test. The mild AIS control group was comprised of AIS patients with NIHSS < 10; the severe AIS control group was comprised of AIS patients with NIHSS ≥10. Mean NIHSS in the severe AIS group was 12.3, similar to the mean NIHSS in the AIS + D group (11.9, Table 1)