Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The mitochondrial lifecycle. Fused mitochondria undergo fission through Fis1. Individual mitochondria can undergo fusion through the actions of Drp1, Opa1, Mfn1, and Mfn2, or can be shuttled to the mitophagy pathway via PINK1 and Parkin. Cellular senescence inhibits mitophagy to induce mitochondrial dysfunction.
