Table 1. Top 10 Gene Ontology (GO) biological process (BP) based on genes with aberrant methylation.
GO | Term | Count | FDR |
---|---|---|---|
GO:0007155 | Cell adhesion | 198 | 6.87E−16 |
GO:0007165 | Signal transduction | 391 | 1.89E−10 |
GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | 339 | 2.41E−10 |
GO:0043547 | Positive regulation of GTPase activity | 210 | 1.12E−08 |
GO:0007156 | Homophilic cell adhesion via plasma membrane adhesion molecules | 79 | 1.36E−08 |
GO:0001525 | Angiogenesis | 96 | 2.43E−06 |
GO:0007399 | Nervous system development | 116 | 3.93E−06 |
GO:0035556 | Intracellular signal transduction | 149 | 2.50E−05 |
GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | 241 | 2.99E−05 |
GO:0060333 | Interferon-gamma-mediated signaling pathway | 38 | 7.91E−04 |