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. 2020 Aug 3;8:e9654. doi: 10.7717/peerj.9654

Table 1. Top 10 Gene Ontology (GO) biological process (BP) based on genes with aberrant methylation.

GO Term Count FDR
GO:0007155 Cell adhesion 198 6.87E−16
GO:0007165 Signal transduction 391 1.89E−10
GO:0045944 Positive regulation of transcription from RNA polymerase II promoter 339 2.41E−10
GO:0043547 Positive regulation of GTPase activity 210 1.12E−08
GO:0007156 Homophilic cell adhesion via plasma membrane adhesion molecules 79 1.36E−08
GO:0001525 Angiogenesis 96 2.43E−06
GO:0007399 Nervous system development 116 3.93E−06
GO:0035556 Intracellular signal transduction 149 2.50E−05
GO:0000122 Negative regulation of transcription from RNA polymerase II promoter 241 2.99E−05
GO:0060333 Interferon-gamma-mediated signaling pathway 38 7.91E−04