eTable 2.
Multivariable Analysis of Factors Associated with Neoadjuvant Endocrine Therapy Receipt
| Patient characteristic | OR (95% CI) | p Value |
|---|---|---|
| Age | ||
| 18–39 y | 1 | Ref |
| 40–49 y | 1.02 (0.73–1.41) | 0.93 |
| 50–59 y | 1.41 (1.02–1.93) | 0.04 |
| 60–69 y | 1.73 (1.26–2.38) | < 0.01 |
| 70–79 y | 1.92 (1.38–2.66) | < 0.01 |
| 80+ y | 2.63 (1.88–3.69) | < 0.01 |
| Race | ||
| White | 1 | Ref |
| Black | 1.06 (0.93–1.21) | 0.38 |
| Hispanic | 1.35 (1.17–1.56) | < 0.01 |
| Asian | 1.07 (0.88–1.30) | 0.50 |
| Charlson Comorbidity Index | ||
| 0 | 1 | Ref |
| 1 | 0.88 (0.79–0.97) | 0.01 |
| 2 | 1.32 (1.10–1.59) | < 0.01 |
| ≥ 3 | 1.83 (1.41–2.39) | < 0.01 |
| Insurance | ||
| Private | 1 | Ref |
| Medicare | 1.16 (1.05–1.29) | < 0.01 |
| Medicaid | 1.47 (1.26–1.70) | < 0.01 |
| Uninsured | 1.53 (1.18–1.99) | < 0.01 |
| Region | ||
| Metro | 1 | Ref |
| Urban | 1.02 (0.91–1.13) | 0.77 |
| Rural | 1.06 (0.81–1.39) | 0.66 |
| Unknown | 1.17 (0.95–1.45) | 0.15 |
| Facility type | ||
| Community | 1 | Ref |
| Comprehensive | 1.13 (0.97–1.30) | 0.11 |
| Academic | 1.62 (1.40–1.87) | < 0.01 |
| Integrated Network | 1.59 (1.36–1.87) | < 0.01 |
| Histology | ||
| Ductal | 1 | Ref |
| Lobular | 1.17 (1.06–1.29) | < 0.01 |
| Mixed | 1.09 (0.98–1.22) | 0.12 |
| Grade | ||
| 1 | 1 | Ref |
| 2 | 0.80 (0.74–0.87) | < 0.01 |
| 3 | 0.45 (0.40–0.51) | < 0.01 |
| cT | ||
| cT1 | 1 | Ref |
| cT2 | 5.40 (5.01–5.81) | <0.01 |
cT, clinical tumor category; OR, odds ratio; Ref, reference.