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. Author manuscript; available in PMC: 2020 Aug 6.
Published in final edited form as: Am J Hematol. 2020 May 7;95(8):906–917. doi: 10.1002/ajh.25831

Figure 1: Time to first treatment by tumor mutational load – CLL overall and stratified by CLL-IPI.

Figure 1:

Kaplan-Meier survival curves with time to first treatment (TTT) by TML of 0 recurrently mutated genes (dashed green), 1 recurrently mutated gene (dotted blue), and 2+ recurrently mutated genes (solid red). (A) TTT Overall with 445 cases; (B) TTT Low to intermediate risk CLL-IPI group with 311 cases; (C) High to very-high risk CLL-IPI group with 128 cases.

CLL, chronic lymphocytic leukemia; CLL-IPI, CLL international prognostic index; TML, tumor mutational load