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. 2020 Jul 13;130(8):4370–4381. doi: 10.1172/JCI137772

Figure 2. Preoperative liking of sucrose-sweetened taste mixtures predicts 6-month weight loss following RYGB.

Figure 2

Weight loss and the relationship between preoperative liking ratings for sucrose+fat-containing mixtures and changes in weight at 6 months following RYGB and VSG. (A) Mean ± SEM %TWL from preoperative/baseline (0 weeks) and 2 weeks, 3 months, and 6 months after surgery in RYGB (red; n = 23) and VSG (blue; n = 25) patients. Repeated-measures ANOVA revealed a main effect of time (F1.4,63.2 = 513.882, P < 0.001), group (F1,46 = 7.956, P = 0.007), and time × group interaction (F1.4,63.2 = 6.024, P = 0.010) for %TWL. *P < 0.05. (B) Preoperative ratings for mixtures with added sucrose correlated with %TWL at 6 months following RYGB (red), but not following VSG (blue). #Significant bivariate correlations. (C) Mean ± SEM %TWL at 6 months following bariatric surgery in patients who gave a “liking” rating from 0 to 100 to half-and-half with 10% added sucrose. One-way ANOVA (F3,44 = 8.093, P < 0.001) with Bonferroni’s correction revealed greater %TWL in RYGB preferrers relative to RYGB nonpreferrers (P = 0.004), VSG preferrers (P < 0.001), and VSG nonpreferrers (P = 0.002). %TWL did not differ between RYGB nonpreferrers, VSG preferrers, and VSG nonpreferrers (P = 1.00). Red, 0–50 VAS liking rating, nonpreferrer, RYGB (n = 15); pink, 51–100 VAS liking rating, preferrer, RYGB (n = 8); blue, 0–50 VAS liking rating, nonpreferrer, VSG (n = 7); cyan, 51–100 VAS liking rating, preferrer, VSG (n = 18).