Table 1.
Clinical characteristics of the subjects
| Patients with T2D N = 48 | Control subjects N = 48 |
p | |
|---|---|---|---|
| General characteristics | |||
| Male, n (%) | 31 (65) | 31 (65) | 1 |
| Age, years: mean (SD) | 64.8 (12.8) | 64.7 (12.8) | 0.2 |
| BMI, kg/m2: mean (SD)a | 27.7 (5.9) | 23.8 (4.9) | < 0.001 |
| Cardiovascular risk factors | |||
| Hypertension, n (%)b | 30 (63) | 13 (29) | 0.013 |
| Dyslipidemia, n (%)c | 32 (76) | 11 (31) | < 0.0001 |
| Coronary disease, n (%)d | 13 (28) | 4 (9) | 0.05 |
| Estimated glomerular filtration rate, mL/min: mean (SD)e | 85.9 (30.3) | 94.9 (23.6) | 0.2 |
| Renal failure, n (%)e | 9 (19) | 3 (7) | 0.2 |
| Severe renal failure, n (%)e | 1 (2) | 0 (0) | 1 |
| Tobacco use (current or stopped for less than 3 years), n (%)f | 11 (25) | 6 (19) | 0.6 |
| Diabetes characteristics | |||
| HbA1c, mmol/mol: median (IQR)g | 58 (48–76) | 34 (33–42) | NA |
| HbA1c, %: median (IQR)g | 7.5 (6.5–9.1) | 5.3 (5.2–6) | NA |
| Diabetes duration, years: median (IQR)h | 10 (5.5–17.3) | ||
| Insulin use, n (%) | 19 (40) | ||
| Neuropathy, n (%)i | 15 (52) | ||
| Nephropathy, n (%)j | 15 (47) | ||
| Retinopathy, n (%)k | 11 (42) | ||
T2D type 2 diabetes, BMI body mass index, SD standard deviation, IQR interquartile range
aAvailable in 45 patients with T2D and 35 control subjects
bAvailable in 47 patients with T2D and 45 control subjects
cAvailable in 42 patients with T2D and 35 control subjects
dAvailable in 46 patients with T2D and 44 control subjects
eGlomerular filtration rate as evaluated by MDRD. Renal failure defined as a GFR < 60 mL/min/1.73 m2. Severe renal failure defined as a GFR < 30 mL/min/1.73 m2. Available in 48 patients with T2D and 46 control subjects
fAvailable in 44 patients with T2D and 32 control subjects
gLast HbA1c in the medical file. Available in 34 patients with T2D and 5 control subjects
hAvailable in 32 patients
iAvailable in 29 patients
jAvailable in 32 patients
kAvailable in 26 patients