Fig 7. HLA-B*35Px restricted CTLs exhibit an exhausted phenotype at the gene level.

(A) Relative mRNA expression of Eomes, (B) T-bet, (C) blimp-1, (D) IL-2, E) IFN-γ and F) TNF-α in CD8⁺ T cells restricted by HLA-B*35Px versus those restricted by HLA-B*27/B57 as quantified by qPCR. Data are from a minimum of five antigen-specific CD8⁺ T cells restricted by each HLA-type and isolated by sorting for RNA isolation and qPCR. Bar, mean ± one standard error.