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. 2020 Jul 27;16(7):e1008774. doi: 10.1371/journal.ppat.1008774

Table 3. gshAB and tlp-C41A mutant reduced carcinogenicity of S. mutans in a gnotobiotic rat model.

Infecting strain	Mean caries scores (n = 5)
	Buccal				Sulcal				Proximal
	E	Ds	Dm	Dx	E	Ds	Dm	Dx	E	Ds	Dm
UA159	34.2 ± 2.01	18.4 ± 1.72	12.2 ± 1.24	5.8 ± 1.02	13.2 ± 0.97	10.2 ± 1.02	7 ± 0.71	4 ± 0.71	10.2 ± 1.24	4.8 ± 1.28	3 ± 0.63
ΔgshAB	13.6 ± 1.78^a	4.8 ± 0.58 ^a	1.8 ± 0.58 ^a	0.6 ± 0.40^b	14.2 ± 1.66	8.2 ± 1.77	5.6 ± 0.93	2.2 ± 0.80	6.8 ± 0.58	1 ± 0.32^d	0.0
tlp-C41A	10.6 ± 1.36^a	3.6 ± 0.81 ^a	1.2 ± 0.37 ^a	0.0	11 ± 1.00	4.4 ± 0.81^d	2.8 ± 0.66^c	0.2 ± 0.20^c	7.2 ± 1.02	1.6 ± 0.51^d	0.0

a: Significantly different from value for group UA159 (P < 0.0001)

b: Significantly different from value for group UA159 (P < 0.001)

c: Significantly different from value for group UA159 (P < 0.01)

d: Significantly different from value for group UA159 (P < 0.05)