Table 1: Replication of rs200342067 association.

We replicated the association between rs200342067 and height in an independently collected cohort (N=598 individuals). We also tested the association of rs200342067 with inverse normally transformed height in two publicly available datasets of Hispanic/Latino individuals (PAGE and GIANT, N=31,214 and 10,776 individuals respectively) and observed a similar direction of effect and effect size in these independent cohorts. P-values are two-sided Wald test p-values. Numbers are rounded to two decimal places.

phenotype	cohort	N	rs	allele1	allele2	MAF (%)	effect size	se	z-score	Wald p-value
Height in cm	Discovery	3,134	rs200342067	C	T	4.72	−2.22	0.36	−6.17	6.8×10−10
	Replication	598	rs200342067	C	T	4.52	−1.70	0.82	−2.07	0.04
	Meta-analysis						−2.14	0.33	−6.48	9.2×10−11
inverse normally transformed height	Discovery	3,134	rs200342067	C	T	4.72	−0.25	0.04	−6.25	4.1×10−10
	Replication	598	rs200342067	C	T	4.52	−0.20	0.10	−2.00	0.05
	PAGE	31,214	rs200342067	C	T	0.37	−0.12	0.07	−1.71	0.09
	GIANT	10,766	rs200342067	C	T	1.15	−0.44	0.22	−2.00	0.05
	Meta-analysis						−0.22	0.03	−6.81	9.8×10−12