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. Author manuscript; available in PMC: 2020 Aug 6.
Published in final edited form as: Biol Psychiatry. 2015 Aug 24;79(9):755–764. doi: 10.1016/j.biopsych.2015.08.018

Figure. 4.

Figure. 4.

Ketamine delays regression of the visual acuity. (A) Example of stimulation used to measure visual acuity by optomotor task (OPT). (B) Average OPT visual in WT-v (n = 14), KO-v (n = 20), KO-k15 (n =11) and KO-k30 (n = 21) mice. Visual acuity was significantly reduced in KO-v (Two-way ANOVA, ** p ≤ 0.01,*** p ≤ 0.001, Bonferroni post-test), whereas ketamine treatment delayed the visual regression. At P55, KO-k15 and KO-k30 acuity was significantly higher than KO-v (Two-way ANOVA, # p ≤ 0.05, Bonferroni post-test), but still statistically lower than WT-v (Two-way ANOVA, * p ≤ 0.05,** p ≤ 0.01, Bonferroni post-test).