Table 3:

Independent predictors of EGFR mutation status

Predictors	EGFR Mutation (Exon 19 + 20 + 21)		EGFR Mutation (Exon 19 + 21)
	OR (95% CI)	P Value	OR (95% CI)	P Value
Female sex	1.630 (0.539–4.927)	.387	1.538 (0.483–4.898)	.466
Age, per 1-yr increase	0.975 (0.928–1.024)	.307	0.972 (0.923–1.024)	.282
Site of BM
Anterior circulation–dominanta	Reference		Reference
Posterior circulation–dominantb	0.750 (0.132–4.250)	.745	0.833 (0.145–4.781)	.837
Even distribution	0.867 (0.275–2.734)	.807	0.741 (0.222–2.471)	.625
No. of BM
1	Reference		Reference
1<BM<10	1.765 (0.491–6.337)	.383	1.765 (0.446–6.979)	.418
≥10	6.000 (0.873–41.214)	.068	7.500 (1.039–54.116)	.045
Target lesion size of BM
<10 mm	Reference		Reference
10 mm≤BM<30 mm	1.015 (0.318–3.243)	.979	0.923 (0.275–3.102)	.897
≥30 mm	1.500 (0.315–7.135)	.61	1.333 (0.260–6.828)	.729
Intratumoral necrosis	1.188 (0.395–3.569)	.759	0.887 (0.273–2.884)	.841
Intratumoral hemorrhage	1.440 (0.382–5.428)	.59	1.412 (0.353–5.649)	.625
Diffusion visual scoring	1.630 (0.680–2.601)	.199	1.514 (0.722–2.974)	.274
ADCmin	0.996 (0.992–1.000)	.028	0.995 (0.991–0.999)	.020
nADC ratio	0.064 (0.006–0.666)	.021	0.044 (0.004–0.563)	.016

^aBMs mainly located in the frontal, parietal, and temporal lobes.

^bBMs mainly located in the occipital lobes, cerebellum, and brain stem.