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Midline sagittal spoiled gradient-recalled acquisition T1WI (1.5T MR imaging; TR/TE = 11/5.1 ms; TI = 500 ms; slice thickness = 1.5 mm) from a 3-month-old girl with CHARGE syndrome shows a distinctive complete coronally oriented clival cleft in the basiocciput (large arrow). Also note mild thinning of the corpus callosum (small arrow), cerebellar vermian hypoplasia, and brain stem volume loss.
