Fig 1.

Imaging characteristics of IDH1-wild type and IDH1-mutant gliomas. A, A 24-year-old woman with an IDH1-wild type lower grade glioma (anaplastic astrocytoma, World Health Organization grade III). The imaging features are as follows: a lobar location, proportion of enhancing tumor of >33%, and poorly defined nonenhancing margin. B, A 42-year-old man with an IDH1-mutant lower grade glioma (anaplastic astrocytoma, WHO grade III). The imaging features are as follows: a lobar location with focal distribution, proportion of enhancing tumor of <33%, and well-defined nonenhancing margin.