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. 2020 Aug 7;288:198113. doi: 10.1016/j.virusres.2020.198113

Table 1.

Relative synonymous codon usage (RSCU) analysis of SARS-CoV-2 and different hosts including human, dog, pig, cattle, pig, cat, horse and Bat. Bold numbers are referred as most preferred codon.

Amino acids Codon SARS CoV-2 Human Dog Cat Pig Horse Cattle Bat
Phenylalanine UUU 1.42 0.93 1.09 0.77 0.75 0.83 0.85 0.49
UUC 0.58 1.07 0.91 1.13 1.25 1.17 1.15 1.01
Leucine UUA 1.66 0.46 1.32 0.35 0.31 0.33 0.38 0.44
UUG 1.06 0.77 0.51 0.76 0.63 0.72 0.71 0.8
CUU 1.75 0.79 1.22 0.67 0.69 0.73 0.7 0.85
CUC 0.57 1.17 1.01 1.29 1.32 1.32 1.26 1.22
CUA 0.68 0.43 1.42 0.36 0.34 0.34 0.36 0.44
CUG 0.28 2.37 0.51 2.57 2.72 2.56 2.59 0.37
Isoleucine AUU 1.54 1.08 1.05 0.95 0.97 0.92 0.98 1.19
AUC 0.54 1.41 0.94 1.58 1.66 1.66 1.57 1.3
AUA 0.92 0.51 1.01 0.47 0.37 0.42 0.45 0.49
Valine GUU 1.93 0.73 1.12 0.62 0.50 0.6 0.64 0.72
GUC 0.58 0.95 0.57 1.13 1.22 1.08 1.01 0.97
GUA 0.89 0.47 1.67 0.38 0.26 0.35 0.4 0.51
GUG 0.59 1.85 0.64 1.87 2.01 1.97 1.95 1.79
Serine UCU 2 1.13 1.35 1.12 0.86 1.09 1.04 1.03
UCC 0.44 1.31 1.04 1.48 1.10 1.43 1.37 1.22
UCA 1.63 0.9 1.27 0.74 1.36 0.8 0.79 0.89
UCG 0.11 0.33 0.39 0.38 0.42 0.34 0.39 0.29
AGU 1.46 0.9 0.91 0.8 0.99 0.86 0.87 0.98
AGC 0.36 1.44 1.05 1.47 1.27 1.48 1.53 1.56
Proline CCU 1.92 1.15 1.41 1.03 0.95 1.19 1.08 1.21
CCC 0.31 1.29 1.24 1.51 0.61 1.38 1.39 1.21
CCA 1.64 1.11 0.92 0.97 0.79 0.97 1 1.23
CCG 0.14 0.45 0.43 0.5 1.65 0.45 0.53 0.35
Threonine ACU 1.77 0.99 1.35 0.84 1.00 0.94 0.89 0.97
ACC 0.39 1.42 1.06 1.59 0.49 1.58 1.55 1.42
ACA 1.65 1.14 1.16 0.94 1.02 0.96 1.01 1.23
ACG 0.19 0.46 0.43 0.63 1.49 0.52 0.56 0.37
Alanine GCU 2.19 1.06 1.07 0.96 1.15 1.05 1 1.12
GCC 0.57 1.6 1.27 1.79 0.44 1.72 1.71 1.57
GCA 1.09 0.91 1.18 0.76 0.41 0.77 0.8 0.94
GCG 0.15 0.42 0.48 0.5 0.70 0.45 0.48 0.35
Tyrosine UAU 1.23 0.89 1.15 0.78 0.75 0.75 0.79 0.87
UAC 0.77 1.11 0.85 1.22 1.25 1.25 1.21 1.12
Histidine CAU 1.43 0.84 1.2 0.74 0.44 0.81 0.75 0.81
CAC 0.57 1.16 0.8 1.26 1.56 1.19 1.25 1.18
Glutamine CAA 1.4 0.53 1.25 0.56 0.78 0.52 0.46 0.49
CAG 0.6 1.47 0.75 1.44 1.22 1.48 1.54 1.5
Asparagine AAU 1.36 0.94 1.18 0.82 0.77 0.84 0.81 0.92
AAC 0.64 1.06 0.82 1.18 1.23 1.16 1.19 1.07
Lysine AAA 1.29 0.87 1.37 0.86 0.74 0.79 0.78 0.84
AAG 0.71 1.13 0.63 1.14 1.26 1.21 1.22 1.15
Aspartic acid GAU 1.29 0.93 1.13 0.84 0.83 0.83 0.84 0.98
GAC 0.71 1.07 0.87 1.16 1.17 1.17 1.16 1.01
Glutamic acid GAA 1.45 0.84 1.17 0.86 0.77 0.76 0.78 1.88
GAG 0.55 1.16 0.83 1.14 1.23 1.24 1.22 1.05
Cysteine UGU 1.59 0.91 0.89 0.87 1.40 0.89 0.85 0.92
UGC 0.41 1.09 1.11 1.13 0.60 1.11 1.15 1.07
Arginine CGU 1.44 0.48 1.17 0.41 0.40 0.55 0.49 0.49
CGC 0.6 1.1 0.92 1.09 0.89 1.15 1.17 0.94
CGA 0.31 0.65 0.71 0.55 0.79 0.61 0.68 0.74
CGG 0.2 1.21 0.48 1.19 1.94 1.08 1.32 1.18
AGA 2.64 1.29 1.29 1.33 1.08 1.3 1.14 1.26
AGG 0.82 1.27 1.42 1.41 0.90 1.32 1.2 1.36
Glycine GGU 2.36 0.65 1.02 0.58 0.58 0.65 0.64 0.71
GGC 0.7 1.35 1.05 1.42 1.17 1.43 1.43 1.36
GGA 0.81 1 1.27 1.01 1.28 0.95 0.95 0.96
GGG 0.12 1 0.66 0.99 0.97 0.97 0.99 0.95