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. 2020 Apr 22;277(9):2573–2580. doi: 10.1007/s00405-020-05963-3

Table 3.

Similar studies that used a cutoff age of 40

Author Year Patients Young group Male:Female in young Survival Prognosis for young group
Young Old
Udeabor et al. [26] 2012 977 3.9% 3.8:1 66.2%/5-y OS 57.6%/5-y OS Better
Van Monsjou et al. [25] 2013 1762 3.1% 1.8:1

58%/5-y OS

69%/5-y DSS

42%/5-y OS

74%/5-y DSS

No significant difference in DSS; better for OS
Fang et al. [43] 2014 176 8.5% 0.7:1 63%5-y DSS 625-y DSS No significant difference
Sun Q [15] 2015 486 7.2% 1.6:1 65%5-y DSS 66.75-y DSS No significant difference
Jae-Ho Jeon et al. [37] 2016 117 20% 1.9:1

40%/5-y OS

42%/5-y DSS

70%/5-y OS

73%/5-y DSS

Worse
Mahmood et al. [11] 2018 115 34.8% 4.7:1 62.5%/5-y OS 37.3%/5-y OS Better
Oliver et al. [20] 2019 22 930 9.9% 1.15:1 79.6%/5-y OS 69.5%/5-y OS Better