Table 1.
Subject demographic and clinical characteristics
| Patient | Gender | Age (years) | BMI (kg/m2) | Pre-therapy sUA (mg/dl) | SubQ tophi | eGFRa (ml/min/1.73 m2) | Comorbidities |
|---|---|---|---|---|---|---|---|
| 1 | Male | 77 | 28.2 | 9.6 | Yes | 37 | HTN, CKD, CAD, DM, DL, lower lid mass |
| 2 | Male | 61 | 27.9 | 9.0 | Yes | 91 | DM, DL, OA, bipolar disorder |
| 3 | Male | 45 | 32.1 | 8.0 | Yes | 111 | HTN, anxiety |
| 4 | Male | 64 | 26.9 | 5.7 | Yes | 59 | CKD |
| 5 | Male | 57 | 25.2 | 8.1 | Yes | 60 | OA |
| 6 | Male | 55 | 30.0 | 11.6 | Yes | 74 | HTN, CKD, DM, OA, DN, history of AKI |
| 7 | Male | 29 | 22.9 | 9.5 | Yes | 106 | HTN, anxiety, polyarthralgia |
| 8 | Female | 40 | 31.5 | 13.1 | Yes | 84 | HTN, rheumatoid arthritis |
| 9 | Male | 49 | 30.2 | 10.6 | Yes | 76 | HTN, OA, kidney stone |
| 10 | Male | 46 | 29.0 | 9.0 | Yes | 86 | HTN, OA, chondrocalcinosis (wrist) |
| Mean ± SD | 52.3 ± 13.5 | 28.4 ± 2.8 | 9.42 ± 2.05 | 10 (100%) | 78.4 ± 22.5 |
sUA serum uric acid levels; SubQ subcutaneous; eGFR estimated glomerular filtration rate; SD standard deviation; HTN hypertension; CAD coronary artery disease; DM diabetes mellitus; DL dyslipidemia; OA osteoarthritis; CKD chronic kidney disease; DN diabetic neuropathy; AKI acute kidney injury
aCalculated using serum creatinine levels using the abbreviated MDRD equation [23]