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. 2020 Jul 31;11:1716. doi: 10.3389/fmicb.2020.01716

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Copyright © 2020 Kumar, Vijaykumar, Dikhit, Abhishek, Mukherjee, Sen, Das and Das.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A,B) Predicted biological processes of upregulated microRNA (miRNA) in G_PKDL with respect to (A) G_THP and (B) G_VL. The interlinked miRNAs and important pathways linked to macrophage effector functions. The interaction of upregulated miRNAs and their targeted biological processes. The highlighted red and green colors denote interlinked miRNAs with key biological processes relevant to macrophage dysfunction such as cytokine response, immune response, etc.